However, 11 of 13 evaluableThis translocation results in the chimeric ASPSCR1TF transcription factor which drives tumorigenesis Complete surgical resection is crucial in allowing a successful outcome in these cases Here, we describe an 11monthold female infant who presented with a wellcircumscribed lesion of the tongue, with the clinical and radiologicASPSCR1TF In order to characterize the fusion gene associated with ASPS and its role in sarcomagenesis, we created a novel mouse allele designed to express ASPSCR1TF conditionally Briefly, the Rosa26LSLAT3 allele was generated by isolating the type 2 ASPSCR1TF fusion gene transcript from total RNA obtained from a human ASPS
Www Cell Com Cancer Cell Pdfextended S1535 6108 14 3
